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Fitch: Adjust the outlook of Uzbekistan to negative.The S&P 500 index fell, and the Nasdaq 100 index rose to 0.6%.Fitch: Adjust the outlook of Uzbekistan to negative.

American natural gas futures fell more than 5% and are now reported at $3.277 per million British heat.Morgan stanley capital international's MSCI Nordic Countries Index fell 1.4%, the worst one-day performance since November 15th, to 376.43 points, with a cumulative decline of more than 2.27% this week. Novo Nordisk closed down 3.9%, the worst performance among the constituent stocks.German regulators investigate potential abuse of electricity price increases.

European natural gas futures fell by more than 11% this week, and the EU carbon tax fell by about 6%. At the end of the European market on Friday (December 13th), ICE UK natural gas futures fell by 3.41% to 102.560p/kcal, with a cumulative decline of 11.49% this week. TTF benchmark Dutch natural gas futures fell 3.57% to 41.030 Euro/MWh, down 11.67% this week. ICE EU carbon emissions trading license (futures price) fell 2.80% to 64.25 euros/ton, down 5.94% this week.The latest research results support Harvard's discovery that Novo Nordisk diet drug Ozempic is related to rare visual loss, and the large-scale test results show that Novo Nordisk diet drug Ozempic is related to rare visual loss, which supports the research results given by Harvard University earlier this year. Obese patients who use Ozempic are more than twice as likely to be diagnosed with NAION. NAION occurs when the blood flow decreases and damages the optic nerve. The risk of eye conditions is still low; Patients should pay attention. Novo Nordisk Denmark's share price once fell more than 3.3%.Major European stock indexes closed down across the board, and major European stock indexes closed down across the board. The German DAX index fell 0.19% to 20386.88 points, up 0.01% this week. The French CAC40 index fell 0.29% to 7399.07 points, down 0.37% this week; Britain's FTSE 100 index fell 0.14% to 8300.33, down 0.1% this week.